Isabel Colón de Toledo was born on 1515 to Diego Columbus (1479 - 01.02.1527) and María de Toledo (1490 - 1549).
the person is recorded as dead but the exact date of death is not entered
Siblings: 3 children, Juana Colón de Toledo (? - 1592), María Colón de Toledo (1510 - ?), Cristóbal Colón de Toledo (1510 - 1571), Luis Colón, 1st Duke of Veragua (1522 - 29.01.1572).